New Research Suggests Grapefruit Can Play a Role in Weight Loss SuccessOne-hundred percent grapefruit juice – a dieter’s friend? A new study, published in Nutrition & Metabolism, concluded that enjoying a pre-meal snack of grapefruit, grapefruit juice or water as part of a reduced-calorie diet can be part of an effective weight loss strategy for obese adults.(1)

Researchers at Vanderbilt University found that obese adults who consumed half a grapefruit, about a half-cup (4.5 ounces) of 100 percent grapefruit juice or about a half-cup (4.5 ounces) of water before three main meals, while on a reduced-calorie diet, experienced significant decreases in weight, body mass index (BMI) and waist circumference. Following the 14-week study, participants experienced an average weight loss of 7.1 percent of their initial body weight. This translates to an average of about 15 pounds per person.

“There’s often a misconception that 100 percent fruit juice should be omitted by those on a weight loss plan,” says Heidi J. Silver, PhD, RD, Assistant Professor of Medicine, Vanderbilt Center for Human Nutrition. “However, this study shows that consumption of a half-cup of 100 percent grapefruit juice led to similar weight loss results as those who chose fresh grapefruit or water as a pre-meal snack three times daily. As with any food or beverage, it’s all about moderation while on a weight loss plan.”

Benefits of Grapefruit and Grapefruit Juice Consumption Go Beyond Weight Loss

While the study shows that participants who consumed a serving of grapefruit or 100 percent grapefruit juice before meals lost the same average weight as those who drank water, these individuals experienced additional potentially significant benefits not reported in the water-drinking group:

  • Increase in HDL cholesterol – Participants who ate half a grapefruit or drank a half-cup of grapefruit juice experienced a significant increase in HDL cholesterol, often referred to as “good” cholesterol – the magnitude of increase in HDL-C could have significant cardiovascular benefits.
  • Decrease in appetite – Those who enjoyed about a half-cup of grapefruit juice as their pre-meal snack reported a significant decrease in appetite.
  • Increase in key nutrient intake Daily consumption of fresh grapefruit or 100 percent grapefruit juice also led to a significant increase in vitamin C intake. Additionally, those who ate half a grapefruit as their pre-meal snack had the added benefit of increasing their fiber intake.

“These findings are noteworthy given that dietary fiber and vitamin C are generally under-consumed by the U.S. population,”(2) adds Gail Rampersaud, MS, RD, LDN, Assistant in Nutrition Research and Education, University of Florida. “Quite often, individuals inadvertently reduce nutrient intake while on a weight loss plan. Grapefruit and 100 percent grapefruit juice are nutrient-rich, making regular consumption an ideal and convenient way to obtain essential vitamins and minerals while maintaining a healthy, reduced-calorie diet.”

The Florida Department of Citrus is an executive agency of Florida government charged with the marketing, research and regulation of the Florida citrus industry. Its activities are funded by a tax paid by growers on each box of citrus that moves through commercial channels. The industry employs nearly 76,000 people, provides an annual economic impact close to $9 billion to the state, and contributes hundreds of millions of dollars in tax revenues that help support Florida’s schools, roads and health care services. For more information about the Florida Department of Citrus, please visit  

The Florida Department of Citrus is an Equal Opportunity Employer and Agency. The Florida Department of Citrus prohibits discrimination in all its programs and activities based on race, color, national origin, gender, religion, age, disability, political beliefs, sexual orientation, and marital and family status. (Not all prohibited bases apply to all programs.)  

(1) Silver HJ, Dietrich MS, Niswender KD. Effects of grapefruit, grapefruit juice and water preloads on energy balance, weight loss, body composition, and cardiometabolic risk in free-living obese adults. Nutrition & Metabolism. 2011;8(8).

(2) U.S. Department of Agriculture and U.S. Department of Health and Human Services. Dietary Guidelines for Americans, 2010. 7th Edition, Washington, DC: U.S. Government Printing Office, December 2010.

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